Redefining Drug Discovery Through Predictive Modelling and Supercomputing Synergy
At the intersection of chemistry, computation, and creativity sits a powerful idea: that the way we discover drugs can – and should – be smarter, faster, and more sustainable. We’re thrilled to announce that Nathan Brown, internationally recognised leader in computational drug discovery, will be delivering the keynote at Sustainable Reality (SR25) this October in London.
Nathan brings decades of experience across academia and industry, with a career defined by practical innovation and a deep commitment to mentorship and collaboration. From pioneering the first multi-objective de novo (“from scratch”) molecular design system to leading computational drug discovery teams at BenevolentAI, Healx, and The Institute of Cancer Research, Nathan has consistently worked at the edge of what’s next, and built the systems to make it real.
Keynote: Catalysts for Change in Digital Chemistry
In this talk, Nathan will trace the evolution of Digital Chemistry over the past 25 years: from a behind-the-scenes function to a central driver of drug discovery. He’ll explore how predictive modelling techniques, from classical QSAR (the method for determining the relationship between chemical structures and biological activity) to quantum computing and LLMs, are being combined in increasingly powerful and sustainable ways to accelerate discovery and reduce experimental waste. His message is clear: the fusion of supercomputing and molecular science is more than just a technical achievement, it’s a catalyst for real-world impact.
The keynote will explore themes including:
- Hybrid Predictive Modelling: Combining classical, physics-based, quantum, and AI-driven methods to enhance accuracy and speed in drug discovery.
- Sustainable Supercomputing: Using automated design and High-Performance Computing (HPC) to reduce experiments, cut resource use, and accelerate time to clinic.
- Collaborative Innovation: Driving progress through community platforms, open science, and empowering the next generation of digital chemists.
Nathan’s talk isn’t just for those in the lab or writing code. It’s for anyone invested in how we build smarter systems that serve science, sustainability, and society.
Join us for Sustainable Reality – October 7th in London – where voices like Nathan’s are shaping the next chapter of HPC, AI, and Quantum for good.